Egyptian woman Eman Ahmed Abd El Aty, 36, used to weigh around 500 kilograms, and prior to the surgery, had not left her house in two decades. But her doctor, Muffazal Lakdawala, told CNN that since Ahmed arrived at the Saifee Hospital in Mumbai last month, she had lost 220 pounds.
Abd El Aty, who is from the Mediterranean port city of Alexandria, was flown to India's commercial capital in a specially modified Airbus on Saturday 11 February for treatment.
The spokesperson told the BBC that she was likely to lose more weight in the coming months.
By age 11, she suffered a stroke and became bed-ridden, after her weight spiked. Because Abd El Aty had no other option left, she tweeted about her problem, and this is how her story got exposure.
"Eman successfully underwent a Laparoscopic Sleeve Gastrectomy on March 7th 2017 at Saifee Hospital".
The doctor added, "She is now on oral fluids and accepting them well".
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Suffering from a thyroid problem, the 37-year-old Eman gained huge weight, which made it impossible for her to move. The next phase of her treatment will involve looking after the associated problems such as diabetes, high blood pressure, hypertension and sleep deprivation.
Abd El Aty was heavier than Pauline Potter, an American who weighed in at 293 kilograms previous year and supposedly worked off her weight through sex marathons.
According to medical experts, Abd El Aty was born at 5kg at birth and was suffering from a disruption of the glands as well as from a parasite called elephantiasis.
Her sister Shaimaa Ahmed and the hospital have initiated a crowd funding campaign to cover the costs of her transport and surgery.
One of the surgeons now treating her, Dr. Muffazal Lakdawala, said he believed Abd El Aty had obsesity-related lymphedema, which also causes swelling, and not elephantiasis. First, her visa request was denied, and she was only granted passage after the direct intervention of India's foreign minister.
Bariatric surgery is a stomach-shrinking bypass procedure carried out on those wanting to lose excessive weight.