The result sees Bayern move to 68 points and still 10 points clear at the top.
The Poland frontman broke the offside trap to latch onto Thiago's through-ball before being hauled down by Burki as he tried to round the Dortmund goalkeeper.
Aaron Hunt fired third-placed Hamburg in front midway through the first half with a free kick inside the far post, only for Matthias Ostrzolek to give away a penalty, which was converted by Andrej Kramaric 10 minutes before the break. "We need him on Wednesday".
The showpiece encounter, broadcast to more than 200 countries, turned out to be a one-sided affair, with Lewandowski taking his league tally to 26 goals in a flawless dress rehearsal ahead of next week's Champions League quarter-final against Real Madrid.
Dortmund visits Bayern Munich in the Bundesliga on Saturday before welcoming French league leader Monaco for the first leg of the Champions League quarterfinals on Tuesday.
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The game comes with few major connotations in the table - Bayern has a 10-point lead on second place Red Bull Leipzig, and Dortmund has a 10-point cushion in fourth place - but the two Bundesliga giants should make for an exciting match. "But it was balanced before his goal". Indeed it may turn out to prove more of a nuisance for fourth-placed Dortmund, who are a point behind Julian Nagelsmann's side as they chance a top-three spot needed for guaranteed entry to next season's Champions League group stage.
Ancelotti was expecting a tough game against "one of the best teams in Europe" coached by "one of the best trainers in the world" in Thomas Tuchel. Taken altogether we had no chance to match Bayern's level today. But in this match, it was Bayern's old guys who got the job done. We were ultimately unable to take points from here.
Der Klassiker is upon us once again as the black and yellows face off against the ruthless Bavarian giants, Bayern Munich, this Saturday.
"When you go two goals down, you have a tough task on your hands". Guerreiro's goal has given Dortmund assurance to reunite in the match after Bayern Munich came close to scoring their third and the visitors were playing considerably better in the closing phases of the first half.
"I'm delighted to have got back on the pitch and I hope I'll now remain fit for a long time".