Residents near Mandeville Canyon and Sullivan Canyon should be ready to go.
As firefighters tenaciously battled flames from several major fires that all flared in just 24 hours in Southern California, animal lovers anxious about their pet's safety with as many as 150,000 people under mandatory evacuation orders.
The blaze was reported at 4:52 a.m. on the east side of the freeway near Mulholland Drive, said Margaret Stewart of the Los Angeles Fire Department.
Residents from Moraga Drive, Linda Flora Drive and Casiano Road down to Bellagio Road have been ordered to evacuate, according to the Los Angeles Police Department.
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Los Angeles Fire Dispatcher Margaret Stewart said the fire could grow with winds blowing at over 25 miles per hour. The Skirball Fire encompasses parts of Bel Air, Holmby Hills, and Brentwood, and is affecting the surrounding food-friendly neighborhoods, including Westwood.
Both were closed for the day, as was Santa Monica College and all schools in the Santa Monica-Malibu school district.
Amid the charred landscape of Little Tujunga Canyon Road in Sylmar on Wednesday stood the remains of Rancho Padilla and the carcasses of almost 30 horses who died in the fast-moving Creek fire.
California is once again on fire, with a blazing inferno - called the Skirball Fire - tearing through the Sepulveda Pass of Los Angeles. Six fixed-wing aircraft and a number of helicopters were deployed to the scene, Garcetti said.
Interstate 405 (I-405) is a major north-south Interstate Highway in Southern California. These closures are causing massive gridlock in what is already one of the city's most congested intersections. Some area restaurants chose to remain open amid the fire and smoke-filled skies, while others closed shop for the day.