"Let's face it", she said.
The first lady's appearance at the conference came as part of her campaign to help children "Be Best", which also includes an emphasis on child well-being overall and opioid addition.
The first lady has raised eyebrows with her "Be Best" campaign that encourages good online behavior, considering her husband's tendency to bully and insult others on Twitter.
During the first lady's remarks, she said that social media services such as Twitter and Facebook "can be destructive and harmful if used incorrectly".
Melania Trump talked up the importance of teaching children positive cyber habits Monday on the same morning that her husband sent tweets deriding current and former USA officials, including one message referring to a former Central Intelligence Agency director as a "political hack".
CNN contributor Kate Andersen Brower agreed with Harlow that she was struck by Melania's mention of "some adults" who engage in cyberbullying as "a veiled message to her husband". "She is well aware of the criticism, but that will not deter her from doing what she feels is right", Grisham said.
"It is exactly what she wants it to be, and has been a success", Mrs. Trump's communications director Stephanie Grisham said.
Her spokeswoman, Stephanie Grisham, said the first lady chose Africa as the destination for her first big solo global trip after she learned about some of the development programs that are underway in many of its countries.
Turkish lira dips again on US sanctions warning
It says the case against Atilla, sentenced to 32 months in prison, was politically motivated. Erdogan has cast the tariffs, and the lira's sell-off, as an "economic war" against Turkey.
Melania Trump pictured at Monday's anti-cyberbullying summit in Rockville, MD.
First Lady Melania Trump delivered a speech Monday morning at the Cyberbullying Prevention Summit in Rockville, Maryland, ironically telling participants how children are more aware of the pitfalls of social media than some adults.
At the same time, President Donald Trump was on Twitter, railing against John Brennan, whom he called a "hack" and "the worst CIA Director in our country's history" as summit panelists discussed the need for adults to be "good digital role models" for children.
Last week, the president referred to his former aide Omarosa Manigault Newman, once the only African-American woman among the senior White House staff, as a "crazed, crying lowlife" and "that dog".
She has acknowledged both the positive and negative impacts of social media.
"By listening to children's ideas and concerns, I believe adults will be better able to help them navigate this often-difficult topic", said Mrs. Trump. She said she was also "inspired by their honest commitment to reducing peer-to-peer bullying through kindness and open communication".
"Bullying is an impediment that must be addressed and stopped, and it has no place in our communities", she said.