The Scot, a three-time champion in Canada, has won three matches in four days at the Citi Open and has said that he might not play his scheduled quarter-final against Australian Alex de Minaur later on Friday.
The Scot had earlier announced that he has chose to sit out next week's Rogers Cup in Toronto and his next tournament will now be the Western and Southern Open, starting on August 13 in Cincinnati. Murray's withdrawal, announced earlier on Friday, gave Australia's Alex de Minaur a free pass to the semi-finals where he will meet the victor of Andrey Rublev and American Denis Kudler. "I don't know how players are expected to recover from that", Murray said.
O'Brien said: "I hope that Andy really takes into consideration this role in his sport and as a global role model to guys and girls on the tour and kids around the world that, when things are hard and tough and the conditions aren't great, it's not OK to just give up". Before the Citi Open began, Murray told reporters, "I'll have to see how the body responds to that".
"I don't think I should be put in a position like that", Murray said immediately after the match.
Murray, whose last prior hardcourt appearance was in March 2017 at Indian Wells, played only two June grasscourt events in his comeback prior to coming to Washington, where he played three of the week's four longest matches.
"I'm giving my view right now as someone who's just come back from a very, very long injury layoff".
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"Finishing matches at 3 in the morning is not good".
He added: "There are lots of positives to take from this week, so I'll take some time to rest and recover - I won't play in Toronto next week - and then head to Cincinnati early to prepare and get ready". Wishing you a speedy recovery. Ranked a career-high 32nd, he reached the fourth round last month at Wimbledon, becoming the first Greek player in the last 16 of a Grand Slam in the Open Era.
"I'm disappointed with that, because I know that the weather's tricky and I know it is for the scheduling, but it's a very hard position to be in".
The week in Washington saw Murray play the most consecutive matches since returning from the hip problem which kept him out for 11 months and he will now have a week's rest and recovery instead of heading to Canada.