Anti-government protests in Romania turned violent on Friday leaving more than 400 people in need of medical attention.
The rally, organized on social media under the motto "Diaspora at Home", called on Romanians living overseas to return home and gather at the square to protest what they say is a corrupt government.
Social media footage shows the protesters assembled on a large street scrambling as the police begin giving chase and shooting tear gas to control the crowd.
The Bucharest-Ilfov Ambulance service said more than 200 people received medical treatment, both protesters and police officers.
Centre-right President Klaus Iohannis said he "strongly condemned the brutal intervention of the police, which was disproportionate to the attitude of most demonstrators", but added that "any form of violence is unacceptable".
"The interior ministry must explain urgently the way it handled tonight's events".
Romania was ranked 49th out of 180 on Transparency International's Corruption Perceptions Index for previous year, below most other European nations.
The protests were organized and promoted by groups of Romanians working overseas, angry at what they say is entrenched corruption, low wages and attempts by the PSD to weaken the judiciary in one of the European Union's most corrupt states. Romania Insider reports that on Friday night, some aggressive protesters, possibly football hooligans, began clashing with police.
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Numerous demonstrators are Romanian expats who have returned from across Europe to voice their anger at the government.
In the last 15 years, around four million people have left Romania, one of the European Union's poorest member states with an average monthly wage of just €520.
The head of the ruling Social Democratic Party, Liviu Dragnea, was sentenced to prison earlier this year for a case related to abuses of power, but he remains in office as the case is appealed.
Another police spokesman, Georgian Enache, said "the legitimate state violence" was justified because protesters had been warned several times to leave the square.
Romanians who live overseas are staging an anti-government protest calling on the left-wing government to resign and an early election.
Protesters briefly clear the center of the square after riot police fired teargas outside the government headquarters, in Bucharest, Romania.
In July, President Iohannis approved the dismissal of anti-corruption prosecutor Laura Codruta Kovesi, who had been leading corruption investigations into local and national politicians. The changes are being challenged in the constitutional court.