If he wins against the Cheeto-in-Chief, Biden would be 78 years old when he assumes office in January 2021. Whereas Bernie Sanders and others favor more socialist-leaning social and fiscal policies, much to the delight of younger constituents, a guy like Biden may be seen as a "safe" liberal who can maintain social order and beat Trump without rocking the boat too much for older Democrats and anti-Trump Republicans.
Biden is the latest of 20 candidates seeking the Democratic nomination, a field that includes senators Bernie Sanders, Elizabeth Warren and Kamala Harris, several current and former members of the House of Representatives and Obama's former cabinet member Julian Castro.
Complicating matters, the last weeks of waiting have been clouded by revelations from multiple women accusing Biden of touching them inappropriately or making them feel uncomfortable with his shows of affection.
Joe Biden enters the Democratic presidential contest as a front-runner, if not the front-runner.
And his fire and passion - he said in 2018 he could "beat the hell out of" Trump - could tap into the country's fractious energy and bolster the case that he is best positioned to defeat the president.
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Responding on "America's Newsroom", Fox News politics editor Chris Stirewalt said Biden's entry into the race ends the "fluffy pink cloud of a Democratic primary", where the candidates have been avoiding attacking each other.
He also has been criticized for his ties to the financial industry, which is prominent in his home state of DE, and for his authorship of a 1994 crime act that led to increased incarceration rates.
Because numerous Democratic Party's biggest donors largely stayed on the sidelines waiting for Biden's decision, the vice president's candidacy will unleash gobs of money into a race that has already been defined by copious amounts of small-dollar contributions.
His first White House bid in 1988 ended after a plagiarism scandal.
Biden gained "some genuine goodwill" with voters over his career, over 36 years as a senator and then eight years as Barack Obama's deputy, said Kondik.
"While we're going to support the Democratic nominee, we can't let a so-called "centrist" like Joe Biden divide the Democratic Party and turn it into the party of 'No, we can't'".