Harris was quick to defend her record as attorney general of California.
It came from New York Mayor Bill de Blasio, who said Biden coddled wealthy donors.
Biden also decidedly rebuked Kirsten Gillibrand's attempts to undermine his record "fighting" for women by noting her past praise of his record.
It was evident that Harris was prepared for an attack from Joe Biden, yet she seemed unprepared for an attack on her record as California's attorney general.
"Everybody's talking about how awful I am on these issues".
The former vice-president also fended off attack from California Senator Kamala Harris, who had ambushed him in the first debate with an unexpectedly strong attack on his race credentials, prefacing his greeting to her with a patronizing "Go easy on me, kid". He took a hit in the polls after that display.
United Kingdom prime minister appoints Brexit supporters to cabinet
But he has since rallied to the Brexit cause and Johnson's leadership challenge after himself bowing out early in the campaign. The purge sent the unequivocal message that Johnson wants to stamp his authority and change the direction of government.
Many top Democratic contenders have made Medicare for All one of their defining issues, with some saying they'd completely take away private insurance. Cory Booker, whom Biden referred to as "the future president" in another tongue-tied slip-up. "Vice President, there's a saying in my community that you're dipping into the Kool-Aid and you don't even know the flavor". Biden wanted to say, text JOE to 30330. The two bickered at length about health care, for one thing. "You can't beat President Trump with double-talk on this plan", Biden told Harris.
You may think Sen. Chris Coons, Democrat of CT.
She put over 1,500 people in jail for marijuana violations, and then laughed about it when she was asked if she'd ever smoked marijuana. Harris did not - claiming later that she was not intimidated by a man who served six terms in the Senate and ran for the White House twice - as she again lit into his prescriptions on healthcare, which was a major talking point on the evening.
Several candidates said they thought Mr Trump should be impeached and others called him a racist.
Booker, asked how he could win states like MI that Trump took in 2016, talked about mobilizing black women, who were integral to some Democratic wins in 2018.
Gov. Jay Inslee of Washington was the most brutal in describing Trump on race: "we can not allow a white nationalist to be in the White House", Inslee said.
Biden looked taken aback and noted that he, too, was a single parent after his wife and child were killed in a vehicle crash - and that both his deceased wife and current wife both worked outside the home.
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